Causes and Prevention of Hypertension

Abstract: Hypertension refers to long-term higher arterial blood pressure. The consistent blood pressure reading of 130/80 or 140/90 mmHg may be hypertension. Essential and secondary hypertension are the two types, 90%-95% of which is essential hypertension with unknown etiology, possibly induced by the interaction of genetic and environmental factors. Secondary hypertension(5%-10%) is caused by some …

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CILSE 2025 Review

On Aug 24th, CILSE 2025(China Life Sciences Conference and Expo) was successfully held in Canton Fair Complex. This event focused on various fields, e.g. biomedicine, molecular diagnosis, antibody drugs, cell and gene therapy, in vitro diagnostics(IVD), mRNA, epigenetics, single cell, proteomics techniques, organoids and organoid chip, analytical biochemistry, biosynthesis, biological imaging, biological services, bioinformatics and …

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Role of E-Cadherin in Cancer

Abstract: Cadherin protein is the important cell surface protein family, including E-Cadherin, N-Cadherin, VE-Cadherin, P-Cadherin, R-Cadherin and K-Cadherin. E-Cadherin is also called intercellular adhesion molecule-1(CDH1) and plays a key role in intercellular junction. CDH1 maintains cell adhesion and complete structure via involving in cell polarity and migration. The general expression in epithelial tissue is important …

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PD-1 and PD-L1 in Cancer

Abstract: Programmed cell death-1(PD-1) and its ligand 1(PD-L1) are important immune checkpoints regulating adaptive immune response. PD-1 consists of 288 amino acids and is mainly expressed in activated T cell, B cell and tumor infiltrating lymphocyte. PD-L1 consists of 290 amino acids and is widely distributed in tumor and antigen presenting cells. They interact with …

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ADLM 2025 Review

On July 31, 2025, the high quality and largest annual laboratory medicine event: 77th Association for Diagnostics & Laboratory Medicine (ADLM) was successfully held in McCormick Place Convention Center, Chicago. FineTest attended the expo at booth 5236, showing the core product line. The great innovations and professional services attracted many professionals. Great Influences This event …

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CILSE 2025

FineTest would like to invite you to visit the company’s booth at CILSE 2025. Location: Area B of the Canton Fair Complex, Guangzhou, China Date: August 22-24, 2025 Booth: Hall 12.2, B30 Your presence is FineTest’s honor, thank you and welcome!

Non-specific Antibody Binding in Flow Cytometry

Abstract: Non-specific antibody binding plays a key role in getting accurate results during flow cytometry. High non-specificity not only produces false positive signal, but also can conceal true biomarkers. Thus, it’s important to identify the source and effects of non-specificity. Optimization of experimental condition, proper antibody selection and strict control can effectively decrease non-specificity and …

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Controls in Flow Cytometry

Abstract: Controls play an important role in flow cytometry. Accurate and reliable results can’t be obtained without proper controls. First, signals are relative(e.g. diffused light and fluorescence signal). Thus, blank or unstained control is required to define signal range. Second, during setting gating of the target cell population, various controls help to determine the gating …

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Targeted Therapy for KLK2 Prostate Cancer

Abstract: Kallikrein 2(KLK2) is the trypsin-like serine protease, about 78% homologous with prostate-specific antigen(PSA). Androgen receptor(AR) regulated-KLK2 is specifically expressed in prostatic epithelial and cancer cells. KLK2 plays an important role in the development of prostate cancer, and relevant to tumor invasion. Thus, KLK2 is considered to be a potential biomarker for prostate cancer targeted …

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Common Blood Tumor Markers

Abstract: Blood tumor markers are biomolecules detecting and monitoring the existence and development of certain types of cancer. They usually evaluate concentration of specific substances in the body via detecting blood sample. The level of these substances may increase when suffering from some tumors. The increased level of markers is not induced by all tumors, …

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