Cytokines

Cytokines

Cytokines are secreted by various cells in the organism to regulate cell growth, differentiation, immune function and physiological activity. Small molecule proteins with high biological activities involve in pathological reactions. pg/ml can take effect.

Advantages

Eukaryotic Expression System: active proteins expressed by mammalian cells like HEK293, CHO etc.

purity
High Purity
SDS PAGE
over 95%
 activity
High Activity
Validated
catalytic activity,
cellular activity
endotoxin level
Low Endotoxin
below 1EU/μg
species
Various Species
Human, Rat
Mouse, Monkey
self-developed
Self-developed
Animal Free
His tag
His Tag
Fc tag and
untagged proteins

ELISA assay comparison between FineTest® P2750 Recombinant CD147 and R&D 972-EMN

Conc.(pg/ml) 7.8125 15.625 31.25 62.5 125 250 500 1000
OD
(450nm)
R&D 0.079 0.308 0.532 0.858 1.377 2.071 2.853 3.383
FineTest® 0.090 0.379 0.624 0.960 1.555 2.297 2.961 3.322
Validated Activity
P8189 Recombinant Human pdgf-A

Activity: Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells.The ED50 for this effect is 60-230 ng/mL in a fluorometric assay.

P8189

P3449 Recombinant Mouse IL-27

Activity: Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 0.6-8 ng/mL.

P3449

Cytokines include interleukins, interferons(IFN), tumor necrosis factors(TNF), colony-stimulating factors(CSF), chemokines, growth factors etc.

Interleukin

Secreted by leukocytes and other immunocytes. Cytokines interact with leukocytes or immunocytes. They play an important role in information transduction, activation and regulation of immunocytes, mediation of T and B cell activation, proliferation, differentiation, inflammatory response etc.

Cat.No Product Name Host Expression Region
P0168 Recombinant Human IL-1b E.Coli 117-269
P0174 Recombinant Human IL-6 E.Coli 29-212
P0180 Recombinant Human IL-8 E.Coli 28-99
P3251 Recombinant Mouse IL-16 E.Coli 1205-1322
P3338 Recombinant Monkey IL-31RA HEK293 cells 1-546
P9720 Recombinant Mouse IL-12A&IL-12B HEK293 cells P43431(23-215)&P43432(23-335)
P9733 Recombinant Human IL-12A&IL-12B HEK293 cells P29460(23-328)&P29459(23-219)
P3449 Recombinant Mouse IL-27 HEK293 Cells O35228(19-228)&Q8K3I6(29-234)
Interferon

Founded in 1957, Interferons were named for interfering virus replication in host cells. They take effects in anti-virus, anti-tumor and immune regulation etc. According to sources and structure, there're three kinds of interferons: IFN-α, IFN-β and IFN-γ, produced by leukocytes, fibroblasts and activated T cells respectively. Biological activity of different IFNs is nearly the same.

Cat.No Product Name Host Expression Region
P2118 Recombinant Human IFNA1 E.Coli 24-189
P4418 Recombinant Human IFNA2 E.Coli 24-188
P2619 Recombinant Human IFNB1 E.Coli 22-187
P0149 Recombinant Human IFNG E.Coli 24-166
Cat.No Product Name Host Expression Region
P0150 Recombinant Mouse IFNG E.Coli 23-155
P0152 Recombinant Rat IFNG E.Coli 23-156
P0146 Recombinant Bovine IFNG E.Coli 24-166
P0147 Recombinant Chicken IFNG E.Coli 20-164
Tumor Necrosis Factor

Named for necrotizing tumor cells. Take effects in immune regulation and tumor killing. Involve in inflammation and fever reaction. According to sources and structure, there're two kinds of TNF: TNF-α and TNF-β, produced by monocyte-macrophage and activated T cells respectively.

Cat.No Product Name Host Expression Region
P4416 Recombinant Human TNFA E.Coli 77-233
P0157 Recombinant Mouse TNFA E.Coli 80-235
P4812 Recombinant Rat TNFA E.Coli 80-235
P0153 Recombinant Bovine TNFA E.Coli 78-234
Cat.No Product Name Host Expression Region
P0154 Recombinant Canine TNFA E.Coli 77-233
P0155 Recombinant Guinea Pig TNFA E.Coli 80-234
P0158 Recombinant Porcine TNFA E.Coli 78-232
P0277 Recombinant Horse TNFA E.Coli 78-234
Colony-Stimulating Factor

Stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells and different hematopoietic progenitor cells. Produce colony-forming cytokines in the semi-solid medium. Different CSFs not only stimulate the proliferation and differentiation of hemopoietic stem cells and progenitor cells in different developmental phases, but also promote the function of mature cells.

Cat.No Product Name Host Expression Region
P9499 Recombinant Human G-CSF HEK293 cells 30-204
P9500 Recombinant Mouse G-CSF HEK293 cells 31-208
P9270 Recombinant Human M-CSF CHO cells 33-190
P9320 Recombinant Mouse M-CSF CHO cells 33-262

Cat.No

Product Name

Host

Expression Region

P8665

Recombinant Human GM-CSF

HEK293 cells

18-144

P9321

Recombinant Mouse GM-CSF

HEK293 cells

18-141

P9699

Recombinant Rat GM-CSF

HEK293 cells

18-144

P9537

Recombinant Human THPO

HEK293 cells

1-353

Chemokine

Chemokines are small protein superfamily binding with G protein coupled receptor on the target cell. Initially found as mediators for directional migration of immunocytes to inflammatory and injury site.

Cat.No Product Name Host Expression Region
P0160 Recombinant Human CCL2 E.Coli 24-99
P0161 Recombinant Mouse CCL2 E.Coli 24-96
P5407 Recombinant Human CCL18 E.Coli 21-89
P5407 Recombinant Human CCL18 E.Coli 21-89
Cat.No Product Name Host Expression Region
P9607 Recombinant Mouse CCL22 E.Coli 25-92
P0164 Recombinant Human CXCL9 E.Coli 23-125
P0207 Recombinant Human CXCL1 E.Coli 35-107
P5299 Recombinant Mouse CXCL5 E.Coli 41-132
Growth Factor

Cytokines capable of stimulating cell growth.

Cat.No Product Name Host Expression Region
P1631 Recombinant Human FGF9 E.Coli 4-208
P1643 Recombinant Human FGF10 E.Coli 38-208
P2602 Recombinant Mouse TGFB1 E.Coli 279-390
P2663 Recombinant Human IGF-1 E.Coli 49-118

Cat.No

Product Name

Host

Expression Region

P2940

Recombinant Human TGFB1

HEK293 cells

30-390

P3046

Recombinant Rat PDGFRB

E.Coli

32-531

P3103

Recombinant Mouse CTGF

E.Coli

26-348

P8133

Recombinant Human VEGF165

HEK293 cells

27-191