Products
Phospho-Akt(Ser473) antibody
References
2
Category:
Research Area:
Synonyms: | RAC-alpha serine/threonine-protein kinase|Protein kinase B (PKB)|Protein kinase B alpha (PKB alpha)|Proto-oncogene c-Akt|RAC-PK-alpha|AKT1|PKB|RAC antibody | ||
Catalogue No.: | FNab06402 | Reactivity: | Human, Mouse, Rat |
Host: | Mouse | Tested Application: | ELISA, IHC, WB |
Clonality: | monoclonal | Isotype: | IgG1 |
- SPECIFICATIONS
- CITATIONS
- FIGURES
- CONDITIONS
- Product Name
- Phospho-Akt(Ser473) antibody
- Catalogue No.
- FNab06402
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 5H4
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- v-akt murine thymoma viral oncogene homolog 1
- Alternative Names
- RAC-alpha serine/threonine-protein kinase|Protein kinase B (PKB)|Protein kinase B alpha (PKB alpha)|Proto-oncogene c-Akt|RAC-PK-alpha|AKT1|PKB|RAC antibody
- UniProt ID
- P31749
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:1000-1:4000; IHC: 1:50-1:200
Validated Images


- Background
- The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification.
IF: 5.2
- Journal:
- Cancers
- Author:
- Group of Experimental Biotherapy and Diagnostics, Institute for Regenerative Medicine, World-Class Research Centre “Digital Biodesign and Personalized Healthcare”, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia
- Cited Date:
- 2023-11-10
- Product:
IF: 3.1
- Journal:
- Naunyn-Schmiedeberg's Archives of Pharmacology
- Author:
- Department of Pharmacology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye.
- Sample:
- MCF-7 cells
- Cited Date:
- 2024-08-02
- Product: