various lysates were subjected to SDS PAGE followed by western blot with FNab10684(GLUT4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart tissue slide using FNab10684( GLUT4 antibody) at dilution of 1:100
Background
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).