Products

anti- BAX antibody

FNab10410 Catalogue No.
Synonyms:
BCL2L4, Apoptosis regulator BAX, BAX
Host:
Rabbit
Reactivity:
Human
Isotype:
IgG
Tested Application:
ELISA, WB
Product Information
Product Name
anti- BAX antibody
Catalogue No.
FNab10410
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Immunogen Information
Immunogen
BCL2-associated X protein
Synonyms
BCL2L4, Apoptosis regulator BAX, BAX
Observed MW
21 kDa
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Uniprot information
UniProt ID
Q07812
Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10410(BAX antibody) at dilution of 1:1000