Products

anti- IL-6 antibody

FNab04282 Catalogue No.
Synonyms
B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- IL-6 antibody
Catalogue No.
FNab04282
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
Immunogen Information
Immunogen
interleukin 6(interferon, beta 2)
Synonyms
B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6
Observed MW
24 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:1000; IHC: 1:50-1:200
Uniprot information
UniProt ID
P05231
Images
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab04282(IL6 Antibody) at dilution of 1:200
Immunofluorescence analysis of RAW264.7 cells using IL-6 antibody (FNab04282) at dilution of 1:100. Blue: DAPI for nuclear staining.
Recombinant protein were subjected to SDS PAGE followed by western blot with FNab04282(Il6 Antibody) at dilution of 1:600