HSD17B8 antibody

Synonyms:(3R)-3-hydroxyacyl-CoA dehydrogenase|17-beta-hydroxysteroid dehydrogenase 8 (17-beta-HSD 8 antibody, HSD17B8)|3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit (KAR alpha subunit)|3-oxoacyl-[acyl-carrier-protein] reductase|Estradiol 17-beta-dehydrogenase 8|Protein Ke6 (Ke6)|Short chain dehydrogenase/reductase family 30C member 1|Testosterone 17-beta-dehydrogenase 8|HSD17B8|FABGL|HKE6|RING2|SDR30C1 antibody
Catalogue No.:FNab04030Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
  • FIGURES
  • CONDITIONS
Product Name
HSD17B8 antibody
Catalogue No.
FNab04030
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
hydroxysteroid(17-beta) dehydrogenase 8
Alternative Names
(3R)-3-hydroxyacyl-CoA dehydrogenase|17-beta-hydroxysteroid dehydrogenase 8 (17-beta-HSD 8 antibody, HSD17B8)|3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit (KAR alpha subunit)|3-oxoacyl-[acyl-carrier-protein] reductase|Estradiol 17-beta-dehydrogenase 8|Protein Ke6 (Ke6)|Short chain dehydrogenase/reductase family 30C member 1|Testosterone 17-beta-dehydrogenase 8|HSD17B8|FABGL|HKE6|RING2|SDR30C1 antibody
UniProt ID
Q92506
Observed MW
34 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab04030(HSD17B8 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human liver using FNab04030(HSD17B8 antibody) at dilution of 1:100
Background
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.