anti- PGK1 antibody 
FNab06354
Catalogue No.
- Synonyms:
- PGKA
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IHC, IF
Product Information
- Product Name
- anti- PGK1 antibody
- Catalogue No.
- FNab06354
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
- The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
Immunogen Information
- Immunogen
- phosphoglycerate kinase 1
- Synonyms
- PGKA
- Observed MW
- 47 kDa
Application
- Tested Application
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Uniprot information
- UniProt ID
- P00558
Images
- Image 1
-
Immunohistochemistry of paraffin-embedded human esophagus using FNab06354 (PGK1 Antibody) at dilution of 1:50
- Image 4
-
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06354 (PGK1 antibody) at dilution of 1:1200
