Products
NFE2L2 antibody

References
7
Category:
Research Area:
Synonyms: | Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2 antibody, NFE2-related factor 2 antibody, Nrf-2)|HEBP1|Nuclear factor antibody, erythroid derived 2 antibody, like 2|NFE2L2|NRF2 antibody | ||
Catalogue No.: | FNab05855 | Reactivity: | Human, Mouse, Rat, Zebrafish |
Host: | Rabbit | Tested Application: | ELISA, IP, WB, IHC, FC |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- CITATIONS
- FIGURES
- CONDITIONS
- Product Name
- NFE2L2 antibody
- Catalogue No.
- FNab05855
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nuclear factor(erythroid-derived 2)-like 2
- Alternative Names
- Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2 antibody, NFE2-related factor 2 antibody, Nrf-2)|HEBP1|Nuclear factor antibody, erythroid derived 2 antibody, like 2|NFE2L2|NRF2 antibody
- UniProt ID
- Q16236
- Observed MW
- 70-100 kDa
Application
- Tested Applications
- ELISA, IP, WB, IHC, FC
- Recommended dilution
- WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500
Validated Images



- Background
- NRF2, also named as NFE2L2, belongs to the bZIP family and CNC subfamily. It is a transcription activator that binds to antioxidant response(ARE) elements in the promoter regions of target genes. NRF2 is important for the coordinated up-regulation of genes in response to oxidative stress. It may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.Nrf2 is a key player in the regulation of genes encoding for many antioxidative response enzymes.The expression of NRF2 may be induced under oxidative stress(PMID:14567983).In lung cancer, Nrf2 activation in malignant cells has been associated with tumor progression and chemotherapy resistance(PMID:20534738). Identifying patients with abnormal NRF2 expression may be important for selection for chemotherapy in NSCLC.
IF: 6.312
- Journal:
- Antioxidants
- Cited Date:
- 2021-07-23
- Product:
IF: 5.1
- Journal:
- Chemico-Biological Interactions
- Author:
- School of Medicine, Yichun University, 576 XueFu Road, Yuanzhou District, Yichun, 336000, PR China
- Cited Date:
- 2024-03-08
- Product:
IF: 5.037
- Journal:
- Life Sciences
- Cited Date:
- 2022-05-27
- Product:
IF: 3.5
- Journal:
- Toxicology Letters
- Author:
- School of Medicine, Yichun University,576 XueFu Road, Yuanzhou District,Yichun 336000,PR China.
- Cited Date:
- 2024-05-17
- Product:
IF: 3.2
- Journal:
- Journal of Biochemical and Molecular Toxicology
- Author:
- Department of Gastroenterology, Ministry of Health Eskisehir City Hospital, Eskisehir, Turkey.
- Cited Date:
- 2025-01-17
- Product:
IF: 2.586
- Journal:
- Tissue and Cell
- Cited Date:
- 2022-08-05
- Product:
- Journal:
- SSRN
- Cited Date:
- 2022-02-11
- Product: