Abstract: Role of Tnf Alpha in cancer can kill and inhibit cytokines of tumor cells. As the important inflammatory mediator, it’s involved in pathologic injury of some autoimmune diseases and promotions for neutrophil phagocytosis, anti-infection against fever, hepatic acute phase protein synthesis, differentiation of myeloid leukemia cell into macrophage, cell proliferation and differentiation etc. Keywords: …
Abstract: GM-CSF (also called CSF2) is a monomeric glycoprotein generated by various cells. Initially, GM-CSF is identified as the hemopoietic factor and functions as a cytokine by secreting macrophage, T cell, mast cell, natural killer cell, endothelial cell and fibroblast. Actually, GM-CSF regulates innate and adaptive immunity as an inflammatory factor instead of the key …
Lysosome Lysosomes are shaped variously and vesicular structures (0.025 to 0.8 micrometers in size) containing numerous hydrolytic enzymes. Their intracellular function is to break down external substances that have entered the cell, as well as to digest portions of the cell’s own cytoplasm or organelles. LAMP1 and LAMP2 are two transmembrane proteins located on the …
Abstract: Organelles are micro-organs which have specific morphology and function in the cytoplasm, mainly including mitochondrion, endoplasmic reticulum, centrosome, chloroplast, ribosome etc. They’re the basic cellular structure and maintain the normal working of the cell. Some organelle markers are specified below. Keywords: Organelle Marker, Ribosome, Endoplasmic Reticulum, Golgi bodies Graph Abstract 1. Ribosome Ribosome …
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1. Overview Isotype control antibodies refer to the immunoglobulin sharing the same species, subtype and dose as the primary antibody. It’s mainly applied in removing the background signal caused by non-specific binding. 2. The Purpose of Isotype Control We know that the antibody structure is divided into a constant region and a variable region. The …
1. Loading Control Antibodies Loading control antibodies are widely used in WB to detect loading control protein expression level and ensure accuracy of experimental results by correcting the error during protein quantitation and sample loading. Besides, loading control can be used as blank control to detect protein transmembrane situation, the staining or ECL process of …
Abstract: Mitochondrion plays an important role in cellular energy metabolism and is the necessary organelle for eukaryote. Mitochondrion has its own genome and is more independent than other organelles like Golgi apparatus, endoplasmic reticulum, lysosomes, ribosome etc. 11 mitochondrial markers are specified below. Keywords: Mitochondrial Marker Antibody, Mitochondrial Protein, Organelle 1. Overview of …
FineTest Validated Antibodies FineTest have 10,000+ antibodies with validated images available for applications like ELISA, WB, IHC, FC..etc, including rabbit polyclonal & mouse monoclonal primary antibodies and various tagged secondary antibodies such as HRP, FITC, Biotin…etc. Primary Antibodies Secondary Antibodies Signal Enhancing Series Antibodies Immunohistochemistry Antibodies Flow Cytometry Antibodies ELISA, WB, IP, IF 10,000+ Options …
FineTest Protein Service FineTest® protein service has supplied nearly over 4,500 proteins expressed by HEK293 and E.Coli for WB, Elisa application. Besides His tag and GST tag, we developed special IF2DI tag with high-efficient solubility which can greatly improve the protein expression. Over 95% Purity Image-based Validation High Throughput Protein Expression and Purification Reproducible Protein …
