HGF antibody

Synonyms:HGF antibody, DFNB39 antibody, F-TCF antibody, HGFB antibody, HPTA antibody, SF antibody
Catalogue No.:FNab10911Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HGF antibody
Catalogue No.
FNab10911
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Immunogen
Immunogen
Hepatocyte growth factor
Alternative Names
HGF antibody, DFNB39 antibody, F-TCF antibody, HGFB antibody, HPTA antibody, SF antibody
UniProt ID
P14210
Observed MW
54 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab10911(HGF Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney tissue using FNab10911(HGF Antibody) at dilution of 1:100
Background
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.