Products
AKR1B1 antibody
- Product Name
- AKR1B1 antibody
- Catalogue No.
- FNab00261
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- aldo-keto reductase family 1, member B1 (aldose reductase)
- Alternative Names
- AKR1B1 antibody, Aldose reductase antibody, AR antibody, ALDR1 antibody, ADR antibody
- UniProt ID
- P15121
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab00261(AKR1B1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat lung using FNab00261(AKR1B1 antibody) at dilution of 1:100
- Background
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
