Products

PKC gamma antibody

Synonyms:PKC gamma antibody, PKCC antibody, PKCG antibody, PRKCG antibody, Protein kinase C gamma type antibody, protein kinase C antibody, gamma antibody, SCA14 antibody
Catalogue No.:FNab10007Reativity:Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
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Product Name
PKC gamma antibody
Catalogue No.
FNab10007
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
protein kinase C, gamma
Alternative Names
PKC gamma antibody, PKCC antibody, PKCG antibody, PRKCG antibody, Protein kinase C gamma type antibody, protein kinase C antibody, gamma antibody, SCA14 antibody
UniProt ID
P63318
Observed MW
78 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:100-1:500
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab10007(PRKCG antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab10007(PRKCG Antibody) at dilution of 1:200
Background
Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
IF: 5.2
Journal:
ASN NEURO
Author:
Department of Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China
Cited Date:
2023-05-05
Product: