Products
Visfatin antibody
- Product Name
- Visfatin antibody
- Catalogue No.
- FNab09412
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nicotinamide phosphoribosyltransferase
- Alternative Names
- 1110035O14Rik antibody, DKFZp666B131 antibody, NAmPRTase antibody, NAMPT antibody, PBEF antibody, PBEF1 antibody, Pre B cell enhancing factor antibody, VF antibody, VISFATIN antibody
- UniProt ID
- P43490
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IP: 1:500-1:2000
Validated Images
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09412(NAMPT Antibody) at dilution of 1:1000
IP result of anti-Visfatin(IP:FNab09412, 4ug; Detection:FNab09412 1:1000) with mouse heart tissue lysate 3720 ug
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab09412(NAMPT antibody) at dilution of 1:50
- Background
- Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
