Products
TRIP10 antibody
- Product Name
- TRIP10 antibody
- Catalogue No.
- FNab08996
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- thyroid hormone receptor interactor 10
- Alternative Names
- Cdc42 interacting protein 4 antibody, CIP4 antibody, HSTP antibody, Protein Felic antibody, Salt tolerant protein antibody, STOT antibody, STP antibody, TR interacting protein 10 antibody, TRIP 10 antibody, TRIP10 antibody
- UniProt ID
- Q15642
- Observed MW
- 75-85 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab08996(TRIP10 antibody) at dilution of 1:2000
- Background
- Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling(By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
