Various lysates were subjected to SDS PAGE followed by western blot with FNab08858( TOM20 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab08858(TOM20 antibody) at dilution of 1:100
Immunofluorescence analysis of HeLa cells using FNab08858(TOM20 antibody) at dilution of 1:100. Blue: DAPI for nuclear staining.
Background
TOMM20, also named as KIAA0016, belongs to the Tom20 family. It is a central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22, TOMM20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. TOMM20 is characterized as major docking receptors to mediate the recognition by different mechanisms.