Products

anti- NRBF2 antibody

FNab05850 Catalogue No.
Synonyms
COPR
Host
Rabbit
Reactivity
Human, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC, IF
Product Information
Product Name
anti- NRBF2 antibody
Catalogue No.
FNab05850
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro) . Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1) . However, effects has been described variably. Involved in the induction of starvation- induced autophagy (PubMed:24785657) . Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 (By similarity) . Proposed to negatively regulate basal and starvation- induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1 (PubMed:25086043) . May be involved in autophagosome biogenesis (PubMed:25086043) . May play a role in neural progenitor cell survival during differentiation (By similarity) .
Immunogen Information
Immunogen
nuclear receptor binding factor 2
Synonyms
COPR
Observed MW
38 kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Uniprot information
UniProt ID
Q96F24
Images
Immunohistochemistry of paraffin-embedded human liver cancer using FNab05850 (NRBF2 Antibody) at dilution of 1:100
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05850 (NRBF2 Antibody) at dilution of 1:1000