Products

anti- MEF2A antibody

FNab05100 Catalogue No.
Synonyms
ADCAD1, mef2, RSRFC4, RSRFC9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB
Product Information
Product Name
anti- MEF2A antibody
Catalogue No.
FNab05100
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Immunogen Information
Immunogen
myocyte enhancer factor 2A
Synonyms
ADCAD1, mef2, RSRFC4, RSRFC9
Observed MW
54kd
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:500 - 1:2000
Uniprot information
UniProt ID
Q02078
Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab05100 (MEF2A antibody) at dilution of 1:1000