Products
IL1B antibody
- Product Name
- IL1B antibody
- Catalogue No.
- FNab04209
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 1, beta
- Alternative Names
- Interleukin-1 beta (IL-1 beta)|Catabolin|IL1B|IL1F2 antibody
- UniProt ID
- P01584
- Observed MW
- 17, 35-40 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab04209( IL1B Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat lung using FNab04209(IL1B antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
