HeLa cells were subjected to SDS PAGE followed by western blot with FNab02738(ELK1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat intestine using FNab02738( ELK1 Antibody) at dilution of 1:100
Immunofluorescence analysis of MCF-7 cells using FNab02738(ELK1 antibody) at dilution of 1:50
Background
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14.