CLPP antibody

Synonyms:CLPP antibody, Endopeptidase Clp antibody
Catalogue No.:FNab01772Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, IP
Clonality:polyclonalIsotype:IgG
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Product Name
CLPP antibody
Catalogue No.
FNab01772
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog
Alternative Names
CLPP antibody, Endopeptidase Clp antibody
UniProt ID
Q16740
Observed MW
26 kDa, 30 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500-1:5000; IP: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:10-1:100
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab01772(CLPP antibody) at dilution of 1:500
IP Result of anti-CLPP(IP: FNab01772, 3μg; Detection: FNab01772, 1:500) with mouse skeletal muscle tissue lysate 3000μg
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab01772(CLPP Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunofluorescent analysis of Hela cells using CLPP antibody FNab01772 at 1:25 dulution
Background
Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides(in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.