Products
BAX antibody
- Product Name
- BAX antibody
- Catalogue No.
- FNab00811
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 5F4
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- BCL2-associated X protein
- Alternative Names
- BCL2L4 antibody
- UniProt ID
- Q07812
- Observed MW
- 21 kDa
Application
- Tested Applications
- ELISA, WB,IHC,IF
- Recommended dilution
- WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab00811(BAX Antibody) at dilution of 1:4000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab00811(BAX Antibody) at dilution of 1:800
- Background
- Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
