Products

AHR antibody

Synonyms:Ah receptor antibody, AHR antibody, aryl hydrocarbon receptor antibody, bHLHe76 antibody
Catalogue No.:FNab00231Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
AHR antibody
Catalogue No.
FNab00231
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
aryl hydrocarbon receptor
Alternative Names
Ah receptor antibody, AHR antibody, aryl hydrocarbon receptor antibody, bHLHe76 antibody
UniProt ID
P35869
Observed MW
105 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00231(AHR antibody) at dilution of 1:1000
IP Result of anti-AHR (IP:FNab00231, 4ug; Detection:FNab00231 1:500) with PC-3 cells lysate 1880ug.
Immunohistochemistry of paraffin-embedded human brain using FNab00231(AHR antibody) at dilution of 1:100
Background
Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.