Products
KHSRP antibody
- Product Name
- KHSRP antibody
- Catalogue No.
- FNab04525
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- KH-type splicing regulatory protein
- Alternative Names
- FBP2 antibody, FUBP2 antibody, FUSE binding protein 2 antibody, KHSRP antibody, KSRP antibody, p75 antibody
- UniProt ID
- Q92945
- Observed MW
- 75 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04525(KHSRP antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human testis using FNab04525(KHSRP antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab04525(KHSRP antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Binds to the dendritic targeting element and may play a role in mRNA trafficking(By similarity). Part of a ternary complex that binds to the downstream control sequence(DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element(FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements(AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
