Products
ACC1 antibody
- Product Name
- ACC1 antibody
- Catalogue No.
- FNab00077
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- acetyl-Coenzyme A carboxylase alpha
- Alternative Names
- ACACA Synonyms ACAC antibody, ACACA antibody, ACC antibody, ACC1 antibody, ACCA antibody, Acetyl CoA carboxylase 1 antibody
- UniProt ID
- Q13085
- Observed MW
- 270 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00077(ACC1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human skeletal muscle using FNab00077(ACC1 antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab00077(ACC1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.
