SOX17 antibody

Synonyms:SOX17 antibody, Transcription factor SOX 17 antibody
Catalogue No.:FNab08124Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
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Product Name
SOX17 antibody
Catalogue No.
FNab08124
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
SRY(sex determining region Y)-box 17
Alternative Names
SOX17 antibody, Transcription factor SOX 17 antibody
UniProt ID
Q9H6I2
Observed MW
44 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:1000
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab08124(SOX17 antibody) at dilution of 1:500
Background
Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells(By similarity).