CX3CR1 antibody

Synonyms:CX3C chemokine receptor 1 (C-X3-C CKR-1 antibody, CX3CR1)|Beta chemokine receptor-like 1 (CMK-BRL-1 antibody, CMK-BRL1)|Fractalkine receptor|G-protein coupled receptor 13|V28|CX3CR1|CMKBRL1|GPR13 antibody
Catalogue No.:FNab10034Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
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Product Name
CX3CR1 antibody
Catalogue No.
FNab10034
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
chemokine(C-X3-C motif) receptor 1
Alternative Names
CX3C chemokine receptor 1 (C-X3-C CKR-1 antibody, CX3CR1)|Beta chemokine receptor-like 1 (CMK-BRL-1 antibody, CMK-BRL1)|Fractalkine receptor|G-protein coupled receptor 13|V28|CX3CR1|CMKBRL1|GPR13 antibody
UniProt ID
P49238
Observed MW
50 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
rat brain were subjected to SDS PAGE followed by western blot with FNab10034(CX3CR1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab10034(CX3CR1 antibody) at dilution of 1:100
Background
Receptor for the CX3C chemokine fractalkine(CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions(PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein(in vitro)(PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1(PubMed:14607932).