Products
SRC antibody
- Product Name
- SRC antibody
- Catalogue No.
- FNab08216
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- v-src sarcoma(Schmidt-Ruppin A-2) viral oncogene homolog
- Alternative Names
- ASV antibody, c SRC antibody, p60 Src antibody, pp60c src antibody, Proto oncogene c Src antibody, SRC antibody, SRC1 antibody
- UniProt ID
- P12931
- Observed MW
- 55kd,60kd
Application
- Tested Applications
- ELISA, IHC, IP, FC, IF, WB
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08216(SRC antibody) at dilution of 1:1000
IP Result of anti-SRC (IP: FNab08216, 5ug; Detection: FNab08216 1:1000) with SH-SY5Y cells lysate 2900ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08216(c-SRC Antibody) at dilution of 1:200
Immunofluorescent analysis of A431 cells using FNab08216 (SRC antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.
