Products
Pre-IL18 antibody
- Product Name
- Pre-IL18 antibody
- Catalogue No.
- FNab06764
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 18(interferon-gamma-inducing factor)
- Alternative Names
- Iboctadekin antibody, IFN gamma inducing factor antibody, IGIF antibody, IL 1 gamma antibody, IL 18 antibody, IL 1g antibody, IL18 antibody, IL1F4 antibody, Interleukin 1 gamma antibody, Interleukin 18 antibody, Mature IL18 antibody, pre IL18 antibody
- UniProt ID
- Q14116
- Observed MW
- 24 kDa
Application
- Tested Applications
- ELISA, WB, IP, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:5000 ; IHC: 1:50-1:500; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06764(Pre-IL18 antibody) at dilution of 1:1000
IP Result of anti-Pre-IL18 (IP:FNab06764, 3ug; Detection:FNab06764 1:1000) with HeLa cells lysate 5000ug.
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab06764(Pre-IL18 Antibody) at dilution of 1:100
Immunofluorescent analysis of HeLa cells using FNab06764 ( Pre-IL18 Antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- Background
- IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.
