Products
PSMD7 antibody
- Product Name
- PSMD7 antibody
- Catalogue No.
- FNab06893
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
- Alternative Names
- 26S proteasome non-ATPase regulatory subunit 7|26S proteasome regulatory subunit RPN8|26S proteasome regulatory subunit S12|Mov34 protein homolog|Proteasome subunit p40|PSMD7|MOV34L antibody
- UniProt ID
- P51665
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06893(PSMD7 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse spleen using FNab06893(PSMD7 antibody) at dilution of 1:100
- Background
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
