Products

PAK1IP1 antibody

Synonyms:PIP1 antibody, WDR84 antibody
Catalogue No.:FNab06121Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PAK1IP1 antibody
Catalogue No.
FNab06121
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
PAK1 interacting protein 1
Alternative Names
PIP1 antibody, WDR84 antibody
UniProt ID
Q9NWT1
Observed MW
44 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab06121(PAK1IP1 antibody) at dilution of 1:1000
Background
Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.