ARG1 antibody

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Synonyms:Arginase-1|Liver-type arginase|Type I arginase|ARG1 antibody
Catalogue No.:FNab10829Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IF, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
  • CITATIONS
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  • CONDITIONS
Product Name
ARG1 antibody
Catalogue No.
FNab10829
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
arginase, liver
Alternative Names
Arginase-1|Liver-type arginase|Type I arginase|ARG1 antibody
UniProt ID
P05089
Observed MW
25-40 kDa
Application
Tested Applications
ELISA, IF, WB
Recommended dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10829(ARG1 antibody) at dilution of 1:1000
Background
Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical?marker?of hepatocellular differentiation in fine needle aspiration cytology and a marker?of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).
IF: 5.8
Journal:
Biomaterials Science
Author:
Department of General Surgery (Hernia and Abdominal Wall Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, China.
Cited Date:
2024-11-22
Product: