Products
CD8 antibody
- Product Name
- CD8 antibody
- Catalogue No.
- FNab10807
- Size
- 100μg
- Form
- liquid
- Purification
- protein A+G purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 2B9
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD8a molecule
- Alternative Names
- CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody
- UniProt ID
- P01732
- Observed MW
- 30 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
Validated Images
MOLT-4 cell lysates were subjected to SDS PAGE followed by western blot with FNab10807(CD8 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab10807(CD8 antibody) at dilution of 1:1000
- Background
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
