Products
GSDMD-N antibody
- Product Name
- GSDMD-N antibody
- Catalogue No.
- FNab10690
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- gasdermin D
- Alternative Names
- Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D antibody, N-terminal (GSDMD-NT antibody, hGSDMD-NTD)|Gasdermin-D antibody, p13|Gasdermin-D antibody, 13 kDa (13 kDa GSDMD)|Gasdermin-D antibody, p40|GSDMD|DFNA5L|GSDMDC1 antibody
- UniProt ID
- P57764
- Observed MW
- 50-53 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:2000
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab10690(GSDMD Antibody) at dilution of 1:1000
- Background
- GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.