Products
BCL2L2 antibody
- Product Name
- BCL2L2 antibody
- Catalogue No.
- FNab10311
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- BCL2-like 2
- Alternative Names
- BCL-W antibody, BCL2-L-2 antibody, BCLW antibody, PPP1R51 antibody
- UniProt ID
- Q92843
- Observed MW
- 21 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab10311(BCL2L2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab10311(BCL2L2 antibody) at dilution of 1:100
- Background
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
