SOD1 antibody

Synonyms:Superoxide dismutase [Cu-Zn] antibody, Superoxide dismutase 1 antibody, hSod1 antibody
Catalogue No.:FNab09989Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SOD1 antibody
Catalogue No.
FNab09989
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
superoxide dismutase 1, soluble
Alternative Names
Superoxide dismutase [Cu-Zn] antibody, Superoxide dismutase 1 antibody, hSod1 antibody
UniProt ID
P00441
Observed MW
16 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09989(SOD1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09989(SOD1 Antibody) at dilution of 1:200
Background
Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.