Products

anti- Collagen Type I antibody

FNab09910 Catalogue No.
Synonyms
Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4
Host
Mouse
Reactivity
Human
Isotype
IgG1
Tested Application
ELISA, IHC
Product Information
Product Name
anti- Collagen Type I antibody
Catalogue No.
FNab09910
Size
100µg
Form
liquid
Purification
protein A+G purified
Purity
≥95% as determined by SDS-PAGE
Host
Mouse
Clonality
monoclonal
Isotype
IgG1
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Immunogen Information
Immunogen
collagen, type I, alpha 2
Synonyms
Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4
Application
Tested Application
ELISA, IHC
Recommended dilution
IHC: 1:2000 - 1:8000
Uniprot information
UniProt ID
P08123
Images
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09910( COL1A2 Antibody) at dilution of 1:5000