Products
SNCA antibody
- Product Name
- SNCA antibody
- Catalogue No.
- FNab09891
- Size
- 100μg
- Form
- liquid
- Purification
- protein A+G purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 5C6
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- synuclein, alpha (non A4 component of amyloid precursor)
- Alternative Names
- Alpha-synuclein|Non-A beta component of AD amyloid|Non-A4 component of amyloid precursor (NACP)|SNCA|NACP|PARK1 antibody
- UniProt ID
- P37840
- Observed MW
- 18 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09891(SNCA antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab09891(SNCA antibody) at dilution of 1:1000
- Background
- Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
