Products

anti- TNF alpha antibody

FNab09822 Catalogue No.
Synonyms
Cachectin, DIF, TNF, TNF a, TNF alpha, TNFA, TNF-a, TNFSF2, Tumor necrosis factor
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- TNF alpha antibody
Catalogue No.
FNab09822
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Immunogen Information
Immunogen
tumor necrosis factor (TNF superfamily, member 2)
Synonyms
Cachectin, DIF, TNF, TNF a, TNF alpha, TNFA, TNF-a, TNFSF2, Tumor necrosis factor
Observed MW
21 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:1000 - 1:2000; IHC: 1:50 - 1:100
Uniprot information
UniProt ID
P01375
Images
Immunohistochemistry of paraffin-embedded human stomach tissue slide using FNab09822 (TNF-a Antibody) at dilution of 1:100.
Hela cells were subjected to SDS PAGE followed by western blot with FNab09822 (TNF-a Antibody) at dilution of 1:1000