CD206 antibody

Synonyms:Macrophage mannose receptor 1 (MMR)|C-type lectin domain family 13 member D|C-type lectin domain family 13 member D-like|Human mannose receptor (hMR)|Macrophage mannose receptor 1-like protein 1|MRC1|CLEC13D|CLEC13DL|MRC1L1 antibody
Catalogue No.:FNab09812Reactivity:Human, Mouse, Rat
Host:MouseTested Application:ELISA, IP, WB
Clonality:monoclonalIsotype:IgG2a
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Product Name
CD206 antibody
Catalogue No.
FNab09812
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
5E3
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
CD206
Alternative Names
Macrophage mannose receptor 1 (MMR)|C-type lectin domain family 13 member D|C-type lectin domain family 13 member D-like|Human mannose receptor (hMR)|Macrophage mannose receptor 1-like protein 1|MRC1|CLEC13D|CLEC13DL|MRC1L1 antibody
UniProt ID
P22897
Observed MW
170 kDa
Application
Tested Applications
ELISA, IP, WB
Recommended dilution
WB: 1:1000-1:4000; IP: 1:200-1:1000
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab09812(CD206 antibody) at dilution of 1:2000
IP Result of anti-CD206 (IP: FNab09812, 5ug; Detection: FNab09812 1:500) with human placenta tissue lysate 1400ug.
Background
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This antibody recognizes the intracellular carboxy-terminal part of CD206 and MRC1L1.
IF: 8.2
Journal:
Cell Communication and Signaling
Author:
Department of Otorhinolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Sample:
THP-1 monocytes
Cited Date:
2024-09-06
Product: