Products
USP9X antibody
- Product Name
- USP9X antibody
- Catalogue No.
- FNab09344
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 9, X-linked
- Alternative Names
- Deubiquitinating enzyme FAF X antibody, DFFRX antibody, FAF antibody, FAM antibody, Fat facets in mammals antibody, hFAM antibody, Ubiquitin thiolesterase FAF X antibody, USP9 antibody, USP9X antibody
- UniProt ID
- Q93008
- Observed MW
- 260-290 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:500-1:5000; IF: 1:10-1:100; IHC: 1：20-1：200; IP: 1：200-1：2000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09344(USP9X antibody) at dilution of 1:500
IP Result of anti-USP9X (IP:FNab09344, 5ug; Detection:FNab09344 1:500) with HEK-293 cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using FNab09344(USP9X Antibody) at dilution of 1:50
- Background
- Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
