human brain tissue were subjected to SDS PAGE followed by western blot with FNab09146(UBA6 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab09146(UBA6 antibody) at dilution of 1:100
Background
Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).