Products
NCR1 antibody
- Product Name
- NCR1 antibody
- Catalogue No.
- FNab10472
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Natural cytotoxicity triggering receptor 1
- Alternative Names
- CD335 antibody, LY94 antibody, NK-p46 antibody, NKP46 antibody, NCR1 antibody
- UniProt ID
- O76036
- Observed MW
- 46 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab10472( NCR1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human skin cancer slide using FNab10472( NCR1 Antibody) at dilution of 1:200
- Background
- The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
