Products
TFB2M antibody
Category:
Research Area:
Synonyms: | Dimethyladenosine transferase 2 antibody, mitochondrial|Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5)|Mitochondrial 12S rRNA dimethylase 2|Mitochondrial transcription factor B2 (h-mtTFB antibody, h-mtTFB2 antibody, hTFB2M antibody, mtTFB2)|S-adenosylmethionine-6-N' antibody, N'-adenosyl(rRNA) dimethyltransferase 2|TFB2M|NS5ATP5 antibody | ||
Catalogue No.: | FNab08622 | Reactivity: | Human, Mouse |
Host: | Rabbit | Tested Application: | ELISA, WB |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- FIGURES
- CONDITIONS
- Product Name
- TFB2M antibody
- Catalogue No.
- FNab08622
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transcription factor B2, mitochondrial
- Alternative Names
- Dimethyladenosine transferase 2 antibody, mitochondrial|Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5)|Mitochondrial 12S rRNA dimethylase 2|Mitochondrial transcription factor B2 (h-mtTFB antibody, h-mtTFB2 antibody, hTFB2M antibody, mtTFB2)|S-adenosylmethionine-6-N' antibody, N'-adenosyl(rRNA) dimethyltransferase 2|TFB2M|NS5ATP5 antibody
- UniProt ID
- Q9H5Q4
- Observed MW
- 45-50 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images

- Background
- S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.