Products

anti- SLC6A4 antibody

FNab10277 Catalogue No.
Synonyms
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, Hsert, SLC6A4, sodium-dependent serotonin transporter, 5HT transporter
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, IHC, WB
Product Information
Product Name
anti- SLC6A4 antibody
Catalogue No.
FNab10277
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Immunogen Information
Immunogen
Solute carrier family 6 member 4
Synonyms
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, Hsert, SLC6A4, sodium-dependent serotonin transporter, 5HT transporter
Observed MW
74 kDa
Application
Tested Application
ELISA, IHC, WB
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
P31645
Images
Immunohistochemistry of paraffin-embedded mouse brain using FNab10277(SLC6A4 antibody) at dilution of 1:100
rat brain were subjected to SDS PAGE followed by western blot with FNab10277(SLC6A4 antibody) at dilution of 1:1000