Products
SLC6A4 antibody
- Product Name
- SLC6A4 antibody
- Catalogue No.
- FNab10277
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Solute carrier family 6 member 4
- Alternative Names
- 5-HTT antibody, 5-HTTLPR antibody, 5HTT antibody, HTT antibody, OCD1 antibody, SERT antibody, SERT1 antibody, Hsert antibody, SLC6A4 antibody, sodium-dependent serotonin transporter antibody, 5HT transporter antibody
- UniProt ID
- P31645
- Observed MW
- 74 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
rat brain were subjected to SDS PAGE followed by western blot with FNab10277(SLC6A4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab10277(SLC6A4 antibody) at dilution of 1:100
- Background
- This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
