Products
STEAP3 antibody
- Product Name
- STEAP3 antibody
- Catalogue No.
- FNab08318
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- STEAP family member 3
- Alternative Names
- TSAP6 antibody
- UniProt ID
- Q658P3
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08318(STEAP3 antibody) at dilution of 1:2000
IP Result of anti-STEAP3 (IP:FNab08318, 4ug; Detection:FNab08318 1:700) with C6 cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab08318(STEAP3 Antibody) at dilution of 1:50
- Background
- Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
