Products
SREBF1 antibody
- Product Name
- SREBF1 antibody
- Catalogue No.
- FNab08220
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sterol regulatory element binding transcription factor 1
- Alternative Names
- BHLHD1 antibody, SREBP1 antibody
- UniProt ID
- P36956
- Observed MW
- 125 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab08220(SREBF1 antibody) at dilution of 1:1000
IP Result of anti-SREBF1 (IP:FNab08220, 4ug; Detection:FNab08220 1:600) with L02 cells lysate 1500ug.
- Background
- Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway(By similarity). Binds to the sterol regulatory element 1(SRE-1)(5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif(5'-ATCACGTGA-3') and to SRE-1(5'-ATCACCCCAC-3').
