Products
Slco4c1 antibody
- Product Name
- Slco4c1 antibody
- Catalogue No.
- FNab07977
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- solute carrier organic anion transporter family, member 4C1
- Alternative Names
- Solute carrier organic anion transporter family member 4C1 (Slco4c1)|Oatp-R|Organic anion transporting polypeptide 4C1 (OATP4C1)|Solute carrier family 21 member 20|Slco4c1|Oatp4c1|Slc21a20 antibody
- UniProt ID
- Q8BGD4
- Observed MW
- 80 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab07977( SLCO4C1 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human kidney using FNab07977(SLCO4C1 antibody) at dilution of 1:100
- Background
- Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.
