Products
Renin receptor,ATP6AP2 antibody
- Product Name
- Renin receptor,ATP6AP2 antibody
- Catalogue No.
- FNab07241
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ATPase, H+ transporting, lysosomal accessory protein 2
- Alternative Names
- APT6M8 9 antibody, ATP6AP2 antibody, ATP6IP2 antibody, ATP6M8 9 antibody, CAPER antibody, ELDF10 antibody, HT028 antibody, M8 9 antibody, MRXE antibody, MSTP009 antibody, N14F antibody, PRR antibody, PSEC0072 antibody, Renin receptor antibody, RENIN RECEPTOR antibody, ATP6AP2 antibody, Renin/prorenin receptor antibody, V ATPase M8.9 subunit antibody, XMRE antibody
- UniProt ID
- O75787
- Observed MW
- 47kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
mouse eye tissue were subjected to SDS PAGE followed by western blot with FNab07241(ATP6AP2 antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab07241(ATP6AP2 Antibody) at dilution of 1:50
- Background
- ATP6AP2, also named as ATP6IP2, CAPER, ELDF10, N14F, ATP6M8-9, Renin receptor and prorenin receptor, is believed to potentiate the renin–angiotensin system(RAS), conferring to prorenin, a likely pathological role at tissue level. The PRR has been identified in the microvascular endothelial cells of the retina, in which it seems to be involved in pathological neovascularization processes. The present study demonstrates for the first time that the PRR is expressed in human ATP6AP2 and suggests a molecular mechanism by which hypertension may exacerbate the pathology of dry AMD.
