mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab06664(PPARD antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab06664(PPARD antibody) at dilution of 1:10
Background
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.